Two gunmen fired on his car in the busy Liaqatabad area, police said. Sabri died on his way to hospital. There was no immediate claim of responsibility.
Sabri was a leading exponent of Sufi devotional music, known as Qawwali.
Sufism, a tolerant, mystical practice of Islam, has millions of followers in Pakistan – but in recent years has come under attack from hard-line Islamists, reports the BBC.
